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Local amplification of GH signalling in target tissue Research Areas What 212+ studies have found The 2026 AAOS systematic review (DeFoor & Dekker, Arthroscopy 2025) examined 22 preclinical mechanism studies and 15 musculoskeletal healing studies for BPC-157, finding consistent positive effects across four muscle transection/crush models and tendon repair models

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[DOI] [PubMed] [Google Scholar] 81.Waldow T., Alexiou K., Witt W., Albrecht S., Wagner F., Knaut M., Matschke K